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Testosterone is an extremely popular and very common anabolic steroid on the market, both within medicine as well as on the anabolic steroid black market across the globe. With regards to the usage of this steroid, testosterone abuse can potentially lead to an overdose and fatal consequences – a very real possibility. Anabolic Steroids And Anion Gap When an anabolic steroid is taken orally, such as testosterone, it undergoes a process called anion gap. Basically, it will not have enough oxygen to complete its body and will end up needing to be excreted through the urine. When an the anabolic steroid is absorbed into the body via the urine, it is in a slightly different position than normal, having its anion gap closed. This is due to the fact that the anabolic steroid has a large volume of water and a large amount of energy stored in its body components that cannot be utilized by the body. A person who takes large amounts of anabolic steroids for a long period of time and does not use good nutritional habits – if only for this duration – will be left with an anion gap with a high volume of water that is very hard for the body to excrete. This anion gap will continue to open over several months. Furthermore, people can get trapped in this anion gap long after the anabolic steroids have broken down or are no longer needed. When taken orally, testosterone is taken into the bloodstream from the liver. Once in the bloodstream of the body, it travels on through the gastrointestinal tract where it will be taken to the muscles via an esterase enzyme. Now we need to break down why an anabolic steroid is able to bypass the anion gap. The Anion Gap Is A Factor of Tryptophan This enzyme is responsible for breaking down taurine (T3) into methionine and homocysteine. Methionine is important in maintaining homocysteine levels so that it doesn't build up and affect the thyroid. Since testosterone is a T3-receptor agonist, it activates this enzyme's activity to make taurine. Also, testosterone has a large amount of taurine in its tissues so it can use this amino acid to complete its metabolic process. A person who is taking large amounts of anabolic steroids for a long period of time and does not use good nutritional habits can be left with an anion gap with a high volume of water that is very hard for the body to excrete. This anion gap will continue to open over several months. Additionally, people can get Similar articles: